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A two-step approach for fluidized bed granulation in pharmaceutical processing: Assessing different models for design and control
Various modeling techniques were used to understand fluidized bed granulation using a two-step approach. First, Plackett-Burman design (PBD) was used to identify the high-risk factors. Then, Box-Behnken design (BBD) was used to analyze and optimize those high-risk factors. The relationship between t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491152/ https://www.ncbi.nlm.nih.gov/pubmed/28662115 http://dx.doi.org/10.1371/journal.pone.0180209 |