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A two-step approach for fluidized bed granulation in pharmaceutical processing: Assessing different models for design and control

Various modeling techniques were used to understand fluidized bed granulation using a two-step approach. First, Plackett-Burman design (PBD) was used to identify the high-risk factors. Then, Box-Behnken design (BBD) was used to analyze and optimize those high-risk factors. The relationship between t...

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Detalles Bibliográficos
Autores principales: Ming, Liangshan, Li, Zhe, Wu, Fei, Du, Ruofei, Feng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491152/
https://www.ncbi.nlm.nih.gov/pubmed/28662115
http://dx.doi.org/10.1371/journal.pone.0180209