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Highly mutable tandem DNA repeats generate a cell wall protein variant more frequent in disease-causing Candida albicans isolates than in commensal isolates

During adaptation to host environments, many microorganisms alter their cell surface. One mechanism for doing so is variation in the number of amino acid repeats in cell surface proteins encoded by hypermutable DNA tandem repeats. In the yeast Candida albicans, an opportunistic human pathogen, the g...

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Detalles Bibliográficos
Autores principales: Zhou, Zhuo, Jordens, Zoe, Zhang, Shuguang, Zhang, Ningxin, Schmid, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491155/
https://www.ncbi.nlm.nih.gov/pubmed/28662107
http://dx.doi.org/10.1371/journal.pone.0180246