SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma

BACKGROUND: SDHD promoter mutations were reported in 4–10% of cutaneous melanomas. The advanced clinico-pathological and patient survival association with SDHD mutation and/or expression in cutaneous melanoma remains controversial. OBJECTIVES: To evaluate the presence of SDHD promoter mutations and...

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Detalles Bibliográficos
Autores principales: Pópulo, Helena, Batista, Rui, Sampaio, Cristina, Pardal, Joana, Lopes, José Manuel, Soares, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491217/
https://www.ncbi.nlm.nih.gov/pubmed/28662141
http://dx.doi.org/10.1371/journal.pone.0180392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491217/
https://www.ncbi.nlm.nih.gov/pubmed/28662141
http://dx.doi.org/10.1371/journal.pone.0180392

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