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Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy
Doxorubicin is a potent chemotherapeutic agent that is widely-used to treat a variety of cancers but causes acute and chronic cardiac injury, severely limiting its use. Clinically, the acute side effects of doxorubicin are mostly manageable, whereas the delayed consequences can lead to life-threaten...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491252/ https://www.ncbi.nlm.nih.gov/pubmed/28662206 http://dx.doi.org/10.1371/journal.pone.0180571 |