Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE

GLUT1 facilitates the down-gradient translocation of D-glucose across cell membrane in mammals. XylE, an Escherichia coli homolog of GLUT1, utilizes proton gradient as an energy source to drive uphill D-xylose transport. Previous studies of XylE and GLUT1 suggest that the variation between an acidic...

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Detalles Bibliográficos
Autores principales: Ke, Meng, Yuan, Yafei, Jiang, Xin, Yan, Nieng, Gong, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491310/
https://www.ncbi.nlm.nih.gov/pubmed/28617850
http://dx.doi.org/10.1371/journal.pcbi.1005603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491310/
https://www.ncbi.nlm.nih.gov/pubmed/28617850
http://dx.doi.org/10.1371/journal.pcbi.1005603

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