Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques

Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics are available to prevent or treat CHIKV infections. We recently isolated a panel of potent...

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Detalles Bibliográficos
Autores principales: Broeckel, Rebecca, Fox, Julie M., Haese, Nicole, Kreklywich, Craig N., Sukulpovi-Petty, Soila, Legasse, Alfred, Smith, Patricia P., Denton, Michael, Corvey, Carsten, Krishnan, Shiv, Colgin, Lois M. A., Ducore, Rebecca M., Lewis, Anne D., Axthelm, Michael K., Mandron, Marie, Cortez, Pierre, Rothblatt, Jonathan, Rao, Ercole, Focken, Ingo, Carter, Kara, Sapparapau, Gopal, Crowe, James E., Diamond, Michael S., Streblow, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491320/
https://www.ncbi.nlm.nih.gov/pubmed/28628616
http://dx.doi.org/10.1371/journal.pntd.0005637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491320/
https://www.ncbi.nlm.nih.gov/pubmed/28628616
http://dx.doi.org/10.1371/journal.pntd.0005637

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