Cargando…
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics are available to prevent or treat CHIKV infections. We recently isolated a panel of potent...
Autores principales: | Broeckel, Rebecca, Fox, Julie M., Haese, Nicole, Kreklywich, Craig N., Sukulpovi-Petty, Soila, Legasse, Alfred, Smith, Patricia P., Denton, Michael, Corvey, Carsten, Krishnan, Shiv, Colgin, Lois M. A., Ducore, Rebecca M., Lewis, Anne D., Axthelm, Michael K., Mandron, Marie, Cortez, Pierre, Rothblatt, Jonathan, Rao, Ercole, Focken, Ingo, Carter, Kara, Sapparapau, Gopal, Crowe, James E., Diamond, Michael S., Streblow, Daniel N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491320/ https://www.ncbi.nlm.nih.gov/pubmed/28628616 http://dx.doi.org/10.1371/journal.pntd.0005637 |
Ejemplares similares
-
Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues
por: Hirsch, Alec J., et al.
Publicado: (2017) -
Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues
por: Hirsch, Alec J., et al.
Publicado: (2017) -
Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses
por: Powers, John M., et al.
Publicado: (2021) -
Nonhuman Primate Models of Chikungunya Virus Infection and Disease (CHIKV NHP Model)
por: Broeckel, Rebecca, et al.
Publicado: (2015) -
Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease
por: Broeckel, Rebecca M., et al.
Publicado: (2019)