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Macrophage migration inhibitory factor downregulation: a novel mechanism of resistance to anti-angiogenic therapy
Anti-angiogenic therapies for cancer such as VEGF neutralizing antibody bevacizumab have limited durability. While mechanisms of resistance remain undefined, it is likely that acquired resistance to anti-angiogenic therapy will involve alterations of the tumor microenvironment. We confirmed increase...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491354/ https://www.ncbi.nlm.nih.gov/pubmed/28218903 http://dx.doi.org/10.1038/onc.2017.1 |