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Inherited determinants of early recurrent somatic mutations in prostate cancer

Prostate cancer is a highly heritable molecularly and clinically heterogeneous disease. To discover germline events involved in prostate cancer predisposition, we develop a computational approach to nominate heritable facilitators of somatic genomic events in the context of the androgen receptor sig...

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Detalles Bibliográficos
Autores principales: Romanel, Alessandro, Garritano, Sonia, Stringa, Blerta, Blattner, Mirjam, Dalfovo, Davide, Chakravarty, Dimple, Soong, David, Cotter, Kellie A., Petris, Gianluca, Dhingra, Priyanka, Gasperini, Paola, Cereseto, Anna, Elemento, Olivier, Sboner, Andrea, Khurana, Ekta, Inga, Alberto, Rubin, Mark A., Demichelis, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491529/
https://www.ncbi.nlm.nih.gov/pubmed/28663546
http://dx.doi.org/10.1038/s41467-017-00046-0