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OP9 Feeder Cells Are Superior to M2-10B4 Cells for the Generation of Mature and Functional Natural Killer Cells from Umbilical Cord Hematopoietic Progenitors

Adoptive natural killer (NK) cell therapy relies on the acquisition of large numbers of mature and functional NK cells. An option for future immunotherapy treatments is to use large amounts of NK cells derived and differentiated from umbilical cord blood (UCB) CD34(+) hematopoietic stem cells (HSCs)...

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Detalles Bibliográficos
Autores principales: Herrera, Lara, Salcedo, Juan Manuel, Santos, Silvia, Vesga, Miguel Ángel, Borrego, Francisco, Eguizabal, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491543/
https://www.ncbi.nlm.nih.gov/pubmed/28713379
http://dx.doi.org/10.3389/fimmu.2017.00755