Antibodies to post-translationally modified insulin as a novel biomarker for prediction of type 1 diabetes in children

AIMS/HYPOTHESIS: We have shown that autoimmunity to insulin in type 1 diabetes may result from neoepitopes induced by oxidative post-translational modifications (oxPTM). Antibodies specific to oxPTM-insulin (oxPTM-INS-Ab) are present in most newly diagnosed individuals with type 1 diabetes and are m...

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Detalles Bibliográficos
Autores principales: Strollo, Rocky, Vinci, Chiara, Napoli, Nicola, Pozzilli, Paolo, Ludvigsson, Johnny, Nissim, Ahuva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491589/
https://www.ncbi.nlm.nih.gov/pubmed/28526919
http://dx.doi.org/10.1007/s00125-017-4296-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491589/
https://www.ncbi.nlm.nih.gov/pubmed/28526919
http://dx.doi.org/10.1007/s00125-017-4296-1

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