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Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung Cancer

Cisplatin (DDP) is currently one of the most commonly used chemotherapeutic drugs for treating ovarian and lung cancer. However, resistance to cisplatin is common and it often leads to therapy failure. In addition, the precise mechanism of cisplatin resistance is still in its infancy. In this study,...

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Detalles Bibliográficos
Autores principales: Zheng, Wujian, Feng, Qi, Liu, Jiao, Guo, Yanke, Gao, Lvfen, Li, Ruiman, Xu, Meng, Yan, Guizhen, Yin, Zhinan, Zhang, Shuai, Liu, Shuangping, Shan, Changliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491617/
https://www.ncbi.nlm.nih.gov/pubmed/28713273
http://dx.doi.org/10.3389/fphar.2017.00421