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Sestrin2 Suppresses Classically Activated Macrophages-Mediated Inflammatory Response in Myocardial Infarction through Inhibition of mTORC1 Signaling

Myocardial infarction (MI) triggers an intense inflammatory response that is essential for dead tissue clearance but also detrimental to cardiac repair. Macrophages are active and critical players in the inflammatory response after MI. Understanding the molecular mechanisms by which macrophage-media...

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Detalles Bibliográficos
Autores principales: Yang, Keping, Xu, Chenhong, Zhang, Yunfeng, He, Shaolin, Li, Dazhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491632/
https://www.ncbi.nlm.nih.gov/pubmed/28713369
http://dx.doi.org/10.3389/fimmu.2017.00728