Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1

Human carboxylesterase 1 (hCE1), one of the most important serine hydrolases distributed in liver and adipocytes, plays key roles in endobiotic homeostasis and xenobiotic metabolism. This study aimed to find potent and selective inhibitors against hCE1 from phytochemicals and their derivatives. To t...

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Detalles Bibliográficos
Autores principales: Zou, Li-Wei, Dou, Tong-Yi, Wang, Ping, Lei, Wei, Weng, Zi-Miao, Hou, Jie, Wang, Dan-Dan, Fan, Yi-Ming, Zhang, Wei-Dong, Ge, Guang-Bo, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491650/
https://www.ncbi.nlm.nih.gov/pubmed/28713276
http://dx.doi.org/10.3389/fphar.2017.00435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491650/
https://www.ncbi.nlm.nih.gov/pubmed/28713276
http://dx.doi.org/10.3389/fphar.2017.00435

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