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Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition

Renal fibrosis, which is a critical pathophysiological event in chronic kidney diseases, is associated with renal epithelial-to-mesenchymal transition (EMT). Epoxyeicosatrienoic acids (EETs) are Cyp epoxygenase arachidonic acid metabolites that demonstrate biological actions that result in kidney pr...

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Detalles Bibliográficos
Autores principales: Skibba, Melissa, Hye Khan, Md. Abdul, Kolb, Lauren L., Yeboah, Michael M., Falck, John R., Amaradhi, Radhika, Imig, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491687/
https://www.ncbi.nlm.nih.gov/pubmed/28713267
http://dx.doi.org/10.3389/fphar.2017.00406