Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation

We recently proved that exosomes engineered in vitro to deliver high amounts of HPV E7 upon fusion with the Nef(mut) exosome-anchoring protein elicit an efficient anti-E7 cytotoxic T lymphocyte immune response. However, in view of a potential clinic application of this finding, our exosome-based imm...

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Detalles Bibliográficos
Autores principales: Di Bonito, Paola, Chiozzini, Chiara, Arenaccio, Claudia, Anticoli, Simona, Manfredi, Francesco, Olivetta, Eleonora, Ferrantelli, Flavia, Falcone, Emiliana, Ruggieri, Anna, Federico, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491702/
https://www.ncbi.nlm.nih.gov/pubmed/28694699
http://dx.doi.org/10.2147/IJN.S131309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491702/
https://www.ncbi.nlm.nih.gov/pubmed/28694699
http://dx.doi.org/10.2147/IJN.S131309

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