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Reducible PEG-POD/DNA Nanoparticles for Gene Transfer In Vitro and In Vivo: Application in a Mouse Model of Age-Related Macular Degeneration

Non-viral gene delivery systems are being developed to address limitations of viral gene delivery. Many of these non-viral systems are modeled on the properties of viruses including cell surface binding, endocytosis, endosomal escape, and nuclear targeting. Most non-viral gene transfer systems exhib...

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Detalles Bibliográficos
Autores principales: Dasari, Bhanu Chandar, Cashman, Siobhan M., Kumar-Singh, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491761/
https://www.ncbi.nlm.nih.gov/pubmed/28918058
http://dx.doi.org/10.1016/j.omtn.2017.06.004