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Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells

INTRODUCTION: Docetaxel is one of the most effective chemotherapeutic agents in the treatment of breast cancer. Breast cancers can have an inherent or acquired resistance to docetaxel but the causes of this resistance remain unclear. However, apoptosis and cell cycle regulation are key mechanisms by...

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Detalles Bibliográficos
Autores principales: Brown, Iain, Shalli, Kawan, McDonald, Sarah L, Moir, Susan E, Hutcheon, Andrew W, Heys, Steven D, Schofield, Andrew C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549179/
https://www.ncbi.nlm.nih.gov/pubmed/15318941
http://dx.doi.org/10.1186/bcr918