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Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells
INTRODUCTION: Docetaxel is one of the most effective chemotherapeutic agents in the treatment of breast cancer. Breast cancers can have an inherent or acquired resistance to docetaxel but the causes of this resistance remain unclear. However, apoptosis and cell cycle regulation are key mechanisms by...
Autores principales: | Brown, Iain, Shalli, Kawan, McDonald, Sarah L, Moir, Susan E, Hutcheon, Andrew W, Heys, Steven D, Schofield, Andrew C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549179/ https://www.ncbi.nlm.nih.gov/pubmed/15318941 http://dx.doi.org/10.1186/bcr918 |
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