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Streptococcus pyogenes Phospholipase A(2) Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice

The Streptococcus pyogenes phospholipase A(2) (SlaA) gene is highly conserved in the M3 serotype of group A S. pyogenes, which often involves hypervirulent clones. However, the role of SlaA in S. pyogenes pathogenesis is unclear. Herein, we report that SlaA induces the expression of intercellular ad...

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Detalles Bibliográficos
Autores principales: Oda, Masataka, Domon, Hisanori, Kurosawa, Mie, Isono, Toshihito, Maekawa, Tomoki, Yamaguchi, Masaya, Kawabata, Shigetada, Terao, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491884/
https://www.ncbi.nlm.nih.gov/pubmed/28713783
http://dx.doi.org/10.3389/fcimb.2017.00300