Cellular uptake and anti-tumor activity of gemcitabine conjugated with new amphiphilic cell penetrating peptides

Gemcitabine (Gem) is used as a single agent or in combination with other anticancer agents to treat many types of solid tumors. However, it has many limitations such as a short plasma half-life, dose-limiting toxicities and drug resistance. Cell-penetrating peptides (CPPs) are short peptides which m...

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Detalles Bibliográficos
Autores principales: Zakeri-Milani, Parvin, Mussa Farkhani, Samad, Shirani, Ali, Mohammadi, Samaneh, Shahbazi Mojarrad, Javid, Akbari, Jafar, Valizadeh, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491906/
https://www.ncbi.nlm.nih.gov/pubmed/28694765
http://dx.doi.org/10.17179/excli2017-249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491906/
https://www.ncbi.nlm.nih.gov/pubmed/28694765
http://dx.doi.org/10.17179/excli2017-249

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