The Cytolethal Distending Toxin Subunit CdtB of Helicobacter hepaticus Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines

Cytolethal distending toxins (CDTs) are common among pathogenic bacteria of the human and animal microbiota. CDTs exert cytopathic effets, via their active CdtB subunit. No clear description of those cytopathic effects has been reported at the cellular level in the target organs in vivo. In the pres...

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Detalles Bibliográficos
Autores principales: Péré-Védrenne, Christelle, Prochazkova-Carlotti, Martina, Rousseau, Benoit, He, Wencan, Chambonnier, Lucie, Sifré, Elodie, Buissonnière, Alice, Dubus, Pierre, Mégraud, Francis, Varon, Christine, Ménard, Armelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491915/
https://www.ncbi.nlm.nih.gov/pubmed/28713773
http://dx.doi.org/10.3389/fcimb.2017.00268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491915/
https://www.ncbi.nlm.nih.gov/pubmed/28713773
http://dx.doi.org/10.3389/fcimb.2017.00268

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