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The Cytolethal Distending Toxin Subunit CdtB of Helicobacter hepaticus Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines
Cytolethal distending toxins (CDTs) are common among pathogenic bacteria of the human and animal microbiota. CDTs exert cytopathic effets, via their active CdtB subunit. No clear description of those cytopathic effects has been reported at the cellular level in the target organs in vivo. In the pres...
Autores principales: | Péré-Védrenne, Christelle, Prochazkova-Carlotti, Martina, Rousseau, Benoit, He, Wencan, Chambonnier, Lucie, Sifré, Elodie, Buissonnière, Alice, Dubus, Pierre, Mégraud, Francis, Varon, Christine, Ménard, Armelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491915/ https://www.ncbi.nlm.nih.gov/pubmed/28713773 http://dx.doi.org/10.3389/fcimb.2017.00268 |
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