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2-pyrazoline derivatives in neuropharmacology: Synthesis, ADME prediction, molecular docking and in vivo biological evaluation

A novel series of 1,3,5-trisubstituted-2-pyrazoline derivatives (PFC-1 to PFC-16) were synthesized in a three step reaction using conventional and microwave assisted green chemistry approach. The synthesized derivatives were characterized and their chemical structures were established by various phy...

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Detalles Bibliográficos
Autores principales: Upadhyay, Savita, Tripathi, Avinash C., Paliwal, Sarvesh, Saraf, Shailendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491920/
https://www.ncbi.nlm.nih.gov/pubmed/28694764
http://dx.doi.org/10.17179/excli2017-250