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Evaluation of central and peripheral effects of doxepin on acetic acid-induced colitis in rat and the involved mechanisms
Anti-colitis effect of antidepressants has been demonstrated recently. Doxepin, a tricyclic antidepressant drug (TCA), with potent H(1), H(2), alpha(1) adrenergic and muscarinic receptor blocking effects could be a good candidate for investigation for its anti-colitis activity. Moreover high prevale...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491921/ https://www.ncbi.nlm.nih.gov/pubmed/28694747 http://dx.doi.org/10.17179/excli2016-727 |