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Evaluation of central and peripheral effects of doxepin on acetic acid-induced colitis in rat and the involved mechanisms

Anti-colitis effect of antidepressants has been demonstrated recently. Doxepin, a tricyclic antidepressant drug (TCA), with potent H(1), H(2), alpha(1) adrenergic and muscarinic receptor blocking effects could be a good candidate for investigation for its anti-colitis activity. Moreover high prevale...

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Detalles Bibliográficos
Autores principales:	Zabihi, Mohsen, Hajhashemi, Valiollah, Talebi, Ardeshir, Minaiyan, Mohsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491921/ https://www.ncbi.nlm.nih.gov/pubmed/28694747 http://dx.doi.org/10.17179/excli2016-727

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