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Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives

Nitrogen-based tetracyclic ortho-quinones (naphtho[1'2':4.5]imidazo[1,2-a]pyridine-5,6-diones, NPDOs) and their nitro-substituted derivatives (nitro-(P)NPDOs) were obtained by condensation of substituted 2,3-dichloro-1,4-naphthoquinones with 2-amino-pyridine and -pyrimidine and nitration a...

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Detalles Bibliográficos
Autores principales: Peciukaityte-Alksne, Milda, Šarlauskas, Jonas, Miseviciene, Lina, Maroziene, Audrone, Cenas, Narimantas, Krikštopaitis, Kastis, Staniulyte, Zita, Anusevicius, Žilvinas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491926/
https://www.ncbi.nlm.nih.gov/pubmed/28694766
http://dx.doi.org/10.17179/excli2017-273