Exploiting Natural Cross-reactivity between Human Immunodeficiency Virus (HIV)-1 p17 Protein and Anti-gp41 2F5 Antibody to Induce HIV-1 Neutralizing Responses In Vivo

Anti-p17 antibodies are able to neutralize human immunodeficiency virus (HIV) entry in a mouse model. In this study, we identified a region of sequence similarity between the epitopes of anti-p17 neutralizing antibodies and anti-gp41 neutralizing 2F5 antibody and verified cross-reactivity between p1...

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Detalles Bibliográficos
Autores principales: Verrier, Bernard, Paul, Stéphane, Terrat, Céline, Bastide, Liza, Ensinas, Agathe, Phelip, Capucine, Chanut, Blandine, Bulens-Grassigny, Laura, Jospin, Fabienne, Guillon, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491952/
https://www.ncbi.nlm.nih.gov/pubmed/28713388
http://dx.doi.org/10.3389/fimmu.2017.00770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491952/
https://www.ncbi.nlm.nih.gov/pubmed/28713388
http://dx.doi.org/10.3389/fimmu.2017.00770

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