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Exploiting Natural Cross-reactivity between Human Immunodeficiency Virus (HIV)-1 p17 Protein and Anti-gp41 2F5 Antibody to Induce HIV-1 Neutralizing Responses In Vivo
Anti-p17 antibodies are able to neutralize human immunodeficiency virus (HIV) entry in a mouse model. In this study, we identified a region of sequence similarity between the epitopes of anti-p17 neutralizing antibodies and anti-gp41 neutralizing 2F5 antibody and verified cross-reactivity between p1...
Autores principales: | Verrier, Bernard, Paul, Stéphane, Terrat, Céline, Bastide, Liza, Ensinas, Agathe, Phelip, Capucine, Chanut, Blandine, Bulens-Grassigny, Laura, Jospin, Fabienne, Guillon, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491952/ https://www.ncbi.nlm.nih.gov/pubmed/28713388 http://dx.doi.org/10.3389/fimmu.2017.00770 |
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