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Pathophysiologic consequences following inhibition of a CFTR-dependent developmental cascade in the lung

BACKGROUND: Examination of late gestation developmental genes in vivo may be limited by early embryonic lethality and compensatory mechanisms. This problem is particularly apparent in evaluating the developmental role of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in the cyst...

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Detalles Bibliográficos
Autores principales: Cohen, J Craig, Larson, Janet E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC549215/
https://www.ncbi.nlm.nih.gov/pubmed/15694001
http://dx.doi.org/10.1186/1471-213X-5-2