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Fibroblast growth factor 2 supports osteoblastic niche cells during hematopoietic homeostasis recovery after bone marrow suppression

BACKGROUND: Hematopoietic stem cell (HSC) maintenance requires a specific microenvironment. HSC niches can be activated by tissue damaging chemotherapeutic drugs and various cell signaling molecules such as SDF-1 and FGF, which might also result in bone marrow stress. Recent research has insufficien...

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Detalles Bibliográficos
Autores principales: Yoon, Kyung-Ae, Son, YeonSung, Choi, Young-Jin, Kim, Joo-Hyun, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492158/
https://www.ncbi.nlm.nih.gov/pubmed/28662672
http://dx.doi.org/10.1186/s12964-017-0181-2