Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation

Heart Failure (HF) is associated with increased circulating levels of aldosterone and systemic inflammation. Mineralocorticoid receptor (MR) antagonists block aldosterone action and decrease mortality in patients with congestive HF. However, the molecular mechanisms underlying the therapeutic benefi...

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Detalles Bibliográficos
Autores principales: Salvador, Ane M., Moss, M. Elizabeth, Aronovitz, Mark, Mueller, Kathleen B., Blanton, Robert M., Jaffe, Iris Z., Alcaide, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492203/
https://www.ncbi.nlm.nih.gov/pubmed/28637706
http://dx.doi.org/10.14814/phy2.13313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492203/
https://www.ncbi.nlm.nih.gov/pubmed/28637706
http://dx.doi.org/10.14814/phy2.13313

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