Cargando…

The thermodynamic basis of glucose‐stimulated insulin release: a model of the core mechanism

A model for glucose sensing by pancreatic β‐cells is developed and compared with the available experimental data. The model brings together mathematical representations for the activities of the glucose sensor, glucokinase, and oxidative phosphorylation. Glucokinase produces glucose 6‐phosphate (G‐6...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilson, David F., Cember, Abigail T. J., Matschinsky, Franz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492210/
https://www.ncbi.nlm.nih.gov/pubmed/28655753
http://dx.doi.org/10.14814/phy2.13327