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The thermodynamic basis of glucose‐stimulated insulin release: a model of the core mechanism
A model for glucose sensing by pancreatic β‐cells is developed and compared with the available experimental data. The model brings together mathematical representations for the activities of the glucose sensor, glucokinase, and oxidative phosphorylation. Glucokinase produces glucose 6‐phosphate (G‐6...
Autores principales: | Wilson, David F., Cember, Abigail T. J., Matschinsky, Franz M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492210/ https://www.ncbi.nlm.nih.gov/pubmed/28655753 http://dx.doi.org/10.14814/phy2.13327 |
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