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Evaluation of Selected CYP51A1 Polymorphisms in View of Interactions with Substrate and Redox Partner
Cholesterol is essential for development, growth, and maintenance of organisms. Mutations in cholesterol biosynthetic genes are embryonic lethal and few polymorphisms have been so far associated with pathologies in humans. Previous analyses show that lanosterol 14α-demethylase (CYP51A1) from the lat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492350/ https://www.ncbi.nlm.nih.gov/pubmed/28713270 http://dx.doi.org/10.3389/fphar.2017.00417 |