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PTEN is a negative regulator of mitotic checkpoint complex during the cell cycle

Nuclear PTEN plays an important role during mitosis. To understand the molecular basis by which PTEN mediates mitotic progression, we examined whether PTEN regulated the formation of mitotic checkpoint complex (MCC). We observed that arsenic trioxide, a mitotic inducer, stimulated nuclear translocat...

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Detalles Bibliográficos
Autores principales: Choi, Byeong H., Xie, Steve, Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492438/
https://www.ncbi.nlm.nih.gov/pubmed/28670501
http://dx.doi.org/10.1186/s40164-017-0079-0