Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis

More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and the tremendous neutrophil burden which persists within the airways; nor why...

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Detalles Bibliográficos
Autores principales: Marteyn, Benoît S., Burgel, Pierre-Régis, Meijer, Laurent, Witko-Sarsat, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492487/
https://www.ncbi.nlm.nih.gov/pubmed/28713772
http://dx.doi.org/10.3389/fcimb.2017.00243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492487/
https://www.ncbi.nlm.nih.gov/pubmed/28713772
http://dx.doi.org/10.3389/fcimb.2017.00243

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