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Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis
More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and the tremendous neutrophil burden which persists within the airways; nor why...
Autores principales: | Marteyn, Benoît S., Burgel, Pierre-Régis, Meijer, Laurent, Witko-Sarsat, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492487/ https://www.ncbi.nlm.nih.gov/pubmed/28713772 http://dx.doi.org/10.3389/fcimb.2017.00243 |
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