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The Metalloprotease, Mpr1, Engages AnnexinA2 to Promote the Transcytosis of Fungal Cells across the Blood-Brain Barrier

Eukaryotic pathogens display multiple mechanisms for breaching the blood-brain barrier (BBB) and invading the central nervous system (CNS). Of the fungal spp., that cause disease in mammals, only some cross brain microvascular endothelial cells which constitute the BBB, and invade the brain. Cryptoc...

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Detalles Bibliográficos
Autores principales: Na Pombejra, Sarisa, Salemi, Michelle, Phinney, Brett S., Gelli, Angie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492700/
https://www.ncbi.nlm.nih.gov/pubmed/28713781
http://dx.doi.org/10.3389/fcimb.2017.00296