Protein and mRNA expression of folic acid-associated enzymes as biomarkers for the cytotoxicity of the thymidylate synthase-targeted drugs, pemetrexed and S-1, in non-small cell lung cancer

The thymidylate synthase (TS)-targeted drugs, pemetrexed and S-1, exert an important role in advanced non-small cell lung cancer (NSCLC) treatment; folic acid-associated enzymes are expected to behave as biomarkers, although their role has yet to be fully elucidated. In the present study, a single-i...

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Detalles Bibliográficos
Autores principales: Kimura, Madoka, Imamura, Fumio, Inoue, Takako, Nishino, Kazumi, Uchida, Junji, Kumagai, Toru, Okami, Jiro, Higasiyama, Masahiko, Kamoshida, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492704/
https://www.ncbi.nlm.nih.gov/pubmed/28685068
http://dx.doi.org/10.3892/mco.2017.1262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492704/
https://www.ncbi.nlm.nih.gov/pubmed/28685068
http://dx.doi.org/10.3892/mco.2017.1262

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