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Resolvin D1 and D2 Reverse Lipopolysaccharide-Induced Depression-Like Behaviors Through the mTORC1 Signaling Pathway

BACKGROUND: Resolvin D1 and D2 are bioactive lipid mediators that are generated from docosahexaenoic acid. Although recent preclinical studies suggest that these compounds have antidepressant effects, their mechanisms of action remain unclear. METHODS: We investigated mechanisms underlying the antid...

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Detalles Bibliográficos
Autores principales: Deyama, Satoshi, Ishikawa, Yuka, Yoshikawa, Kotomi, Shimoda, Kento, Ide, Soichiro, Satoh, Masamichi, Minami, Masabumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492780/
https://www.ncbi.nlm.nih.gov/pubmed/28419244
http://dx.doi.org/10.1093/ijnp/pyx023