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Discontinuation, Efficacy, and Safety of Cholinesterase Inhibitors for Alzheimer’s Disease: a Meta-Analysis and Meta-Regression of 43 Randomized Clinical Trials Enrolling 16 106 Patients

BACKGROUND: We investigated the effect of cholinesterase inhibitors on all-cause discontinuation, efficacy and safety, and the effects of study design-, intervention-, and patient-related covariates on the risk-benefit of cholinesterase inhibitors for Alzheimer’s disease. METHODS: A systematic revie...

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Detalles Bibliográficos
Autores principales: Blanco-Silvente, Lídia, Castells, Xavier, Saez, Marc, Barceló, Maria Antònia, Garre-Olmo, Josep, Vilalta-Franch, Joan, Capellà, Dolors
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492783/
https://www.ncbi.nlm.nih.gov/pubmed/28201726
http://dx.doi.org/10.1093/ijnp/pyx012