The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells

The microtubule (MT)-associated protein Tau is a natively unfolded protein, involved in a number of neurodegenerative disorders, collectively called tauopathies, aggregating in neurofibrillary tangles (NFT). It is an open question how the conversion from a MT bound molecule to an aggregation-prone T...

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Detalles Bibliográficos
Autores principales: Di Primio, Cristina, Quercioli, Valentina, Siano, Giacomo, Rovere, Matteo, Kovacech, Branislav, Novak, Michal, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492851/
https://www.ncbi.nlm.nih.gov/pubmed/28713242
http://dx.doi.org/10.3389/fnmol.2017.00210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492851/
https://www.ncbi.nlm.nih.gov/pubmed/28713242
http://dx.doi.org/10.3389/fnmol.2017.00210

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