Intratumoral Lentivector-Mediated TGF-β1 Gene Downregulation As a Potent Strategy for Enhancing the Antitumor Effect of Therapy Composed of Cyclophosphamide and Dendritic Cells

Vaccination with dendritic cells (DCs) stimulated with tumor antigens can induce specific cellular immune response that recognizes a high spectrum of tumor antigens. However, the ability of cancer cells to produce immunosuppressive factors drastically decreases the antitumor activity of DCs. The mai...

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Detalles Bibliográficos
Autores principales: Rossowska, Joanna, Anger, Natalia, Szczygieł, Agnieszka, Mierzejewska, Jagoda, Pajtasz-Piasecka, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492852/
https://www.ncbi.nlm.nih.gov/pubmed/28713366
http://dx.doi.org/10.3389/fimmu.2017.00713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492852/
https://www.ncbi.nlm.nih.gov/pubmed/28713366
http://dx.doi.org/10.3389/fimmu.2017.00713

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