Cargando…

Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain

BACKGROUND: Moloney leukemia virus 10 (Mov10) is an RNA helicase that mediates access of the RNA-induced silencing complex to messenger RNAs (mRNAs). Until now, its role as an RNA helicase and as a regulator of retrotransposons has been characterized exclusively in cell lines. We investigated the ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Skariah, Geena, Seimetz, Joseph, Norsworthy, Miles, Lannom, Monica C., Kenny, Phillip J., Elrakhawy, Mohamed, Forsthoefel, Craig, Drnevich, Jenny, Kalsotra, Auinash, Ceman, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492891/
https://www.ncbi.nlm.nih.gov/pubmed/28662698
http://dx.doi.org/10.1186/s12915-017-0387-1