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Apoptosis Induced via Gamma Delta T Cell Antigen Receptor “Blocking” Antibodies: A Cautionary Tale

Mechanistic studies contribute greatly to our understanding of γδ T cell (γδTc) biology, aiding development of these cells as immunotherapeutic agents. The antibody blocking assay is an accepted method to determine the receptors involved in γδTc killing of tumor targets. Effectors and/or targets are...

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Detalles Bibliográficos
Autores principales: Dutta, Indrani, Postovit, Lynne-Marie, Siegers, Gabrielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492911/
https://www.ncbi.nlm.nih.gov/pubmed/28713391
http://dx.doi.org/10.3389/fimmu.2017.00776