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Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders

Ageing is the main risk factor for human neurological disorders. Among the diverse molecular pathways that govern ageing, epigenetics can guide age-associated decline in part by regulating gene expression and also through the modulation of genomic instability and high-order chromatin architecture. E...

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Detalles Bibliográficos
Autores principales: Delgado-Morales, Raúl, Agís-Balboa, Roberto Carlos, Esteller, Manel, Berdasco, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493012/
https://www.ncbi.nlm.nih.gov/pubmed/28670349
http://dx.doi.org/10.1186/s13148-017-0365-z