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Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders
Ageing is the main risk factor for human neurological disorders. Among the diverse molecular pathways that govern ageing, epigenetics can guide age-associated decline in part by regulating gene expression and also through the modulation of genomic instability and high-order chromatin architecture. E...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493012/ https://www.ncbi.nlm.nih.gov/pubmed/28670349 http://dx.doi.org/10.1186/s13148-017-0365-z |