Re-evaluation of SNP heritability in complex human traits

SNP heritability, the proportion of phenotypic variance explained by SNPs, has been reported for many hundreds of traits. Its estimation requires strong prior assumptions about the distribution of heritability across the genome, but the assumptions in current use have not been thoroughly tested. By...

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Detalles Bibliográficos
Autores principales: Speed, Doug, Cai, Na, Johnson, Michael R., Nejentsev, Sergey, Balding, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493198/
https://www.ncbi.nlm.nih.gov/pubmed/28530675
http://dx.doi.org/10.1038/ng.3865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493198/
https://www.ncbi.nlm.nih.gov/pubmed/28530675
http://dx.doi.org/10.1038/ng.3865

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