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Dysregulation of H/ACA ribonucleoprotein components in chronic lymphocytic leukemia
Telomeres are protective repeats of TTAGGG sequences located at the end of human chromosomes. They are essential to maintain chromosomal integrity and genome stability. Telomerase is a ribonucleoprotein complex containing an internal RNA template (hTR) and a catalytic subunit (hTERT). The human hTR...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493334/ https://www.ncbi.nlm.nih.gov/pubmed/28666010 http://dx.doi.org/10.1371/journal.pone.0179883 |