HA117 endows HL60 cells with a stem-like signature by inhibiting the degradation of DNMT1 via its ability to down-regulate expression of the GGL domain of RGS6

All-trans retinoic acid (ATRA) induces complete remission in almost all patients with acute promyelocytic leukemia (APL) via its ability to induce the in vivo differentiation of APL blasts. However, prolonged ATRA treatment can result in drug resistance. In previous studies, we generated a multi-dru...

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Detalles Bibliográficos
Autores principales: Li, Shuangshuang, Jin, Xianqing, Wu, Huan, Wang, Yi, Li, Xiaoqing, Guo, Yuxia, Liang, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493346/
https://www.ncbi.nlm.nih.gov/pubmed/28665981
http://dx.doi.org/10.1371/journal.pone.0180142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493346/
https://www.ncbi.nlm.nih.gov/pubmed/28665981
http://dx.doi.org/10.1371/journal.pone.0180142

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